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N-, Alpha-, and Beta-Substituted 3-Aminopropionic acids: Design, syntheses and antiseizure activities

The Jarisch-Herxheimer reaction

Metabolomics services were performed by the Metabolomics Core Facility, immune characterization by the Immunotherapy Assessment Core Facility, and sequencing by the NUSeq Core Facility at Robert H

H., Li, S., Vanderstichel, R., Miller, K

10.3390/cancers10120483 74 LeeJ.-H.YooE.-S.HanS.-H.JungG.-H.HanE.-J.JungS.-H.et al (2021a)

Moreover, inflammatory mediators, such as Nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) and Tumor necrosis factor-alpha (TNF-) increased, while pivotal proteins involved in dendritic and synaptic development, such as Synaptophysin (SYP), postsynaptic density protein 95 (PSD95) and brain-derived neurotrophic factor (BDNF) decreased in APP/PS1 mice